Team: Cycling Team Le Sud (Jeroen Henkelman)
| Voornaam | Achternaam | Team | Punten |
| Mathieu | VAN DER POEL | Alpecin-Deceuninck | 52 |
| Phil | BAUHAUS | Bahrain - Victorious | 25 |
| Mikel | LANDA | Soudal - Quick Step | 20 |
| Wilco | KELDERMAN | Team Visma | Lease a bike | 22 |
| Guilhamme | MARTIN | Groupama - FDJ | 9 |
| Arnaud | DEMARE | Arkea - B&B Hotels | 69 |
| Atilla | VALTER | Team Visma | Lease a bike | 7 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 51 |
| Biniam | GIRMAY | Intermarché - Wanty | 53 |
| Giacomo | NIZZOLO | Israel Premier Tech | 18 |
| Caleb | EWAN | INEOS Grenadiers | 21 |
| Alejandro | VALVERDE | Movistar Team | 10 |
| Mark | CAVENDISH | Astana Qazaqstan Team | 41 |
| Simon | YATES | Team Visma | Lease a bike | 30 |
| Romain | BARDET | Team dsm-firmenich PostNL | 19 |
| Tom | DUMOULIN | Team Visma | Lease a bike | 16 |
| Fernando | GAVIRIA | Movistar Team | 42 |
| Giulio | CICCONE | Lidl - Trek | 24 |
| Joao | ALMEIDA | UAE Team Emirates | 20 |
Etappe 1: Boedapest – Visegrád 06-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mathieu | VAN DER POEL | Alpecin-Deceuninck | 15 |
| Wilco | KELDERMAN | Team Visma | Lease a bike | 6 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 5 |
| Biniam | GIRMAY | Intermarché - Wanty | 12 |
Etappe 2: Boedapest – Boedapest 07-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mathieu | VAN DER POEL | Alpecin-Deceuninck | 12 |
| Wilco | KELDERMAN | Team Visma | Lease a bike | 4 |
| Simon | YATES | Team Visma | Lease a bike | 15 |
| Tom | DUMOULIN | Team Visma | Lease a bike | 9 |
Etappe 3: Kaposvár – Balatonfüred 08-05-2022
| Voornaam | Achternaam | Team | Punten |
| Phil | BAUHAUS | Bahrain - Victorious | 1 |
| Arnaud | DEMARE | Arkea - B&B Hotels | 12 |
| Biniam | GIRMAY | Intermarché - Wanty | 7 |
| Caleb | EWAN | INEOS Grenadiers | 3 |
| Mark | CAVENDISH | Astana Qazaqstan Team | 15 |
| Fernando | GAVIRIA | Movistar Team | 9 |
Etappe 4: Avola – Etna 10-05-2022
| Voornaam | Achternaam | Team | Punten |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 4 |
| Romain | BARDET | Team dsm-firmenich PostNL | 3 |
| Joao | ALMEIDA | UAE Team Emirates | 1 |
Etappe 5: Catania – Messina 11-05-2022
| Voornaam | Achternaam | Team | Punten |
| Phil | BAUHAUS | Bahrain - Victorious | 5 |
| Arnaud | DEMARE | Arkea - B&B Hotels | 15 |
| Biniam | GIRMAY | Intermarché - Wanty | 6 |
| Giacomo | NIZZOLO | Israel Premier Tech | 9 |
| Fernando | GAVIRIA | Movistar Team | 12 |
Etappe 6: Palmi – Scalea 12-05-2022
| Voornaam | Achternaam | Team | Punten |
| Phil | BAUHAUS | Bahrain - Victorious | 5 |
| Arnaud | DEMARE | Arkea - B&B Hotels | 15 |
| Biniam | GIRMAY | Intermarché - Wanty | 7 |
| Giacomo | NIZZOLO | Israel Premier Tech | 6 |
| Caleb | EWAN | INEOS Grenadiers | 12 |
| Mark | CAVENDISH | Astana Qazaqstan Team | 9 |
Etappe 7: Diamante – Potenza 13-05-2022
| Voornaam | Achternaam | Team | Punten |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 1 |
| Alejandro | VALVERDE | Movistar Team | 2 |
| Tom | DUMOULIN | Team Visma | Lease a bike | 7 |
| Joao | ALMEIDA | UAE Team Emirates | 3 |
Etappe 8: Napels – Napels 14-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mathieu | VAN DER POEL | Alpecin-Deceuninck | 4 |
| Guilhamme | MARTIN | Groupama - FDJ | 2 |
| Biniam | GIRMAY | Intermarché - Wanty | 6 |
Etappe 9: Isernia – Blockhaus 15-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mikel | LANDA | Soudal - Quick Step | 7 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 9 |
| Alejandro | VALVERDE | Movistar Team | 2 |
| Romain | BARDET | Team dsm-firmenich PostNL | 12 |
| Joao | ALMEIDA | UAE Team Emirates | 6 |
Etappe 10: Pescara – Jesi 17-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mathieu | VAN DER POEL | Alpecin-Deceuninck | 12 |
| Wilco | KELDERMAN | Team Visma | Lease a bike | 7 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 6 |
| Biniam | GIRMAY | Intermarché - Wanty | 15 |
| Romain | BARDET | Team dsm-firmenich PostNL | 4 |
| Joao | ALMEIDA | UAE Team Emirates | 2 |
Etappe 11: Santarcangelo di Romagna – Reggio Emilia 18-05-2022
| Voornaam | Achternaam | Team | Punten |
| Phil | BAUHAUS | Bahrain - Victorious | 2 |
| Arnaud | DEMARE | Arkea - B&B Hotels | 7 |
| Caleb | EWAN | INEOS Grenadiers | 6 |
| Mark | CAVENDISH | Astana Qazaqstan Team | 5 |
| Fernando | GAVIRIA | Movistar Team | 12 |
Etappe 12: Parma – Genua 19-05-2022
| Voornaam | Achternaam | Team | Punten |
| Wilco | KELDERMAN | Team Visma | Lease a bike | 5 |
Etappe 13: San Remo – Cuneo 20-05-2022
| Voornaam | Achternaam | Team | Punten |
| Phil | BAUHAUS | Bahrain - Victorious | 12 |
| Arnaud | DEMARE | Arkea - B&B Hotels | 15 |
| Giacomo | NIZZOLO | Israel Premier Tech | 3 |
| Mark | CAVENDISH | Astana Qazaqstan Team | 9 |
| Fernando | GAVIRIA | Movistar Team | 7 |
Etappe 14: Santena – Turijn 21-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mikel | LANDA | Soudal - Quick Step | 4 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 9 |
| Simon | YATES | Team Visma | Lease a bike | 15 |
| Joao | ALMEIDA | UAE Team Emirates | 5 |
Etappe 15: Rivarolo Canavese – Cogne 22-05-2022
| Voornaam | Achternaam | Team | Punten |
| Guilhamme | MARTIN | Groupama - FDJ | 1 |
| Giulio | CICCONE | Lidl - Trek | 15 |
Etappe 16: Salò – Aprica 24-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mikel | LANDA | Soudal - Quick Step | 5 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 7 |
| Alejandro | VALVERDE | Movistar Team | 6 |
| Joao | ALMEIDA | UAE Team Emirates | 3 |
Etappe 17: Ponte di Legno – Lavarone 25-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mikel | LANDA | Soudal - Quick Step | 1 |
| Guilhamme | MARTIN | Groupama - FDJ | 2 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 6 |
Etappe 18: Borgo Valsugana – Treviso 26-05-2022
| Voornaam | Achternaam | Team | Punten |
| Arnaud | DEMARE | Arkea - B&B Hotels | 5 |
| Mark | CAVENDISH | Astana Qazaqstan Team | 3 |
| Fernando | GAVIRIA | Movistar Team | 2 |
Etappe 19: Marano Lagunare – Castelmonte 27-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mikel | LANDA | Soudal - Quick Step | 1 |
| Guilhamme | MARTIN | Groupama - FDJ | 4 |
| Atilla | VALTER | Team Visma | Lease a bike | 7 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 3 |
Etappe 20: Belluno – Fedaiapas/Marmolada 28-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mikel | LANDA | Soudal - Quick Step | 2 |
| Giulio | CICCONE | Lidl - Trek | 9 |
Etappe 21: Verona – Verona 29-05-2022
| Voornaam | Achternaam | Team | Punten |
| Mathieu | VAN DER POEL | Alpecin-Deceuninck | 9 |
| Richard | CARAPAZ MONTENEGRO | EF Education EasyPost | 1 |